Jarid1c polyclonal antibody

Jarid1c polyclonal antibodyis available at Gentaur for Next week Delivery.

Description: Jarid1c is a histone demethylase which specifically demethylates lysine 4 of histone H3, thereby playing a central role in the regulation of transcription and chromatin remodelling. Jarid1c demethylates the trimethylated and dimethylated lysine 4, but not the monomethylated form. Further, Jarid1c participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Mutations in the Jarid1c gene have been associated with X-linked mental retardation.

Immunogen Sequence:Polyclonal antibody raised in rabbit against mouse Jarid1c (jumonji, AT rich interactive domain 1C), using 3 KLH-conjugated synthetic peptides containing sequences from the inner part of the protein.

Target Alternative Name:KDM5C, MRXJ, MRXSJ, SMCX, XE169

Species Reactivities:Human, mouse.

Tag Line:Polyclonal Antibody to detect Jarid 1c in human and mouse samples.

Formulation:In PBS with 0.05% (W/V) sodium azide.

Purification: Whole Anti-Sera

Application:Western blot, ELISA.

Positive Control:Western blot: HeLa cells, ELISA: Peptides.

Application And Usages:Western Blot: 1:1000, ELISA: 1:500.

Handling:The antibody solution should be gently mixed before use.