IL-10 Antibody

IL-10 Antibodyis available at Gentaur for Next week Delivery.

Description: IL-10 (Interleukin-10), originally known as Cytokine Synthesis Inhibitory Factor (CSIF), is an 20.5 kDa protein containing 161-178 amino acid residues. IL10 is produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.

Immunogen Sequence:Recombinant human protein

Target Alternative Name:CSIF, IL-10, IL10A, TGIF, B-TCGF, GVHDS, mgC126450, mgC126451, RP11-262N9.1, Interleukin-10

Species Reactivities:Human, mouse, rat

Tag Line:Polyclonal Antibody to detect IL-10 in human, mouse and rat samples

Formulation:30 µg (0.5 mg/ml) of antibody in PBS containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH7.2

Purification: Affinity Purified Antibody

Application:Western blot

Positive Control:Western Blot: Jurkat cell lysate

Application And Usages:Western blot: 1:200

Handling:The antibody solution should be gently mixed before use.