IKKalpha/IKK-1 Antibody

IKKalpha/IKK-1 Antibodyis available at Gentaur for Next week Delivery.

Description: IKKα (IkB kinase-α or IKK-1) is part of a large protein complex responsible for the inducible phosphorylation of IkB proteins. Human IKK-α is an 85 kDa peptide that has been shown to activate NFkB by phosphorylation of IkB proteins. IKKα interacts with its upstream kinase, NIK, and its downstream substrate, the IkB proteins. Mutations of IKKα in its kinase domain lead to a dominant-negative phenotype that suppresses TNF-α and IL-1β induced NFkB activation.

Immunogen Sequence:E. coli expressed recombinant human IKKa

Target Alternative Name:IKK-alpha, IKKA, IKK-A, IKBKA, NFKBIKA, TCF16, CHUK, IKK1

Species Reactivities:Human

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Formulation:100 µg (0.5 mg/ml) Protein A purified rabbit anti-IKKα polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunoprecipitation

Positive Control:/

Application And Usages:Western blot (at 0.5-1 µg/ml) and immunoprecipitation (4-8 µg/ml). However, the optimal conditions should be determined individually.

Handling:The antibody solution should be gently mixed before use.