IKKalpha/IKK-1 Antibody

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SKU:
3185-100
£179.27
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Description

IKKalpha/IKK-1 Antibodyis available at Gentaur for Next week Delivery.

Description: IKKα (IkB kinase-α or IKK-1) is part of a large protein complex responsible for the inducible phosphorylation of IkB proteins. Human IKK-α is an 85 kDa peptide that has been shown to activate NFkB by phosphorylation of IkB proteins. IKKα interacts with its upstream kinase, NIK, and its downstream substrate, the IkB proteins. Mutations of IKKα in its kinase domain lead to a dominant-negative phenotype that suppresses TNF-α and IL-1β induced NFkB activation.

Immunogen Sequence:E. coli expressed recombinant human IKKa

Target Alternative Name:IKK-alpha, IKKA, IKK-A, IKBKA, NFKBIKA, TCF16, CHUK, IKK1

Species Reactivities:Human

Tag Line:/

Formulation:100 µg (0.5 mg/ml) Protein A purified rabbit anti-IKKα polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunoprecipitation

Positive Control:/

Application And Usages:Western blot (at 0.5-1 µg/ml) and immunoprecipitation (4-8 µg/ml). However, the optimal conditions should be determined individually.

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
100 µg
Antibody Target:
IKKa/IKK-1
Category:
IKKa
Lot Number:
50985
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
NP_001269
Gene Id:
1147
Concentration:
0.5 mg/ml
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
China
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Not Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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