HNF-4 Antibody

HNF-4 Antibodyis available at Gentaur for Next week Delivery.

Description: HNF-4 (Hepatocyte nuclear factor 4), a member of the steroid/thyroid nuclear receptor superfamily, is a transcriptional factor which expresses in the liver, intestine, kidney, and pancreatic cells. It contains several functional domains: a ligand-independent activation domain (AF1), a zinc finger DNA binding domain, and a ligand-dependent activation domain (AF2). HNF-4 binds to a specific DNA element as a homodimer and regulates the expression of many genes, involved in glucose, fatty acid, and cholesterol metabolisms.

Immunogen Sequence:Synthetic peptide surrounding amino acid 454 of rat HNF

Target Alternative Name:HNF4A , TCF , MODY 1 , MODY , TCF14 , FLJ39654 , HNF4 , HNF 4

Species Reactivities:Mouse, rat

Tag Line:/

Formulation:30 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Mouse small intestine and rat kidney (Cat.# 2702-100) tissue lysates can be used as positive controls.

Handling:The antibody solution should be gently mixed before use.