Histone Methyltransferase (SUV39H1) Antibody

Histone Methyltransferase (SUV39H1) Antibodyis available at Gentaur for Next week Delivery.

Description: The histone methyltransferase KMT1A / SUV39H1 is the mammalian homologue of the Drosophila PEV modifier Su(var)3-9 protein. SUV39H1 contains the SET and chromo domains. In eukaryotic cells, SUV39H1 and the methyl-lysine binding protein HP1 interact to repress transcription at heterochromatic sites. SUV39H1 methylates histone H3 on lysine 9, which generates a binding site for HP1 proteins that plays a role in heterochromatin formation and gene silencing.

Immunogen Sequence:Synthetic peptide surrounding amino acid 389 of mouse Histone Methyltransferase.

Target Alternative Name:Histone-lysine N-methyltransferase, SUV39H1, Histone H3-K9 methyltransferase 1, H3-K9-HMTase 1, Full=Position-effect variegation 3-9 homolog, Suppressor of variegation 3-9 homolog 1, Su(var)3-9 homolog 1

Species Reactivities:Human, mouse, rat, drosophila

Tag Line:/

Formulation:30 µg (0.5 mg/ml) affinity purified rabbit anti-Histone transferase polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal

Purification: Affinity purified

Application:Western blot

Positive Control:3T3 cell lysate

Application And Usages:Western blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually. 3T3 cell lysate can be used as a positive control.

Handling:The antibody solution should be gently mixed before use.