H3K36me1 polyclonal antibody

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SKU:
6817-25
€245
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Description

H3K36me1 polyclonal antibodyis available at Gentaur for Next week Delivery.

Description: Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called “histone code”. Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases.

Immunogen Sequence:KLH-conjugated synthetic peptide of Histone H3 containing monomethylated lysine 36.

Target Alternative Name:Histone H3

Species Reactivities:Human.

Tag Line:Polyclonal Antibody to detect H3K36me1 in human samples.

Formulation:In PBS with 0.05% sodium azide and 0.05% ProClin 300.

Purification: Affinity purified

Application:Western blot, IF, ELISA, ChIP, Dot blot.

Positive Control:Western blot: HeLa cells, IF: U2OS cells, ELISA: Antigen, ChIP: HeLa cells, Dot blot: Histone Peptides.

Application And Usages:WB: 1:1000, ELISA: 1:100, Dot Blot: 1:20,000, IF: 1:500, ChIP: 5 µg/ChIP.

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
25 μg
Antibody Target:
H3K36me1
Category:
H3K36me1
Lot Number:
9H276817
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
P68431
Gene Id:
8350
Concentration:
N/A
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Not Verified
Immunofluorescence Verified:
Verified
Immunoprecipitation Verified:
Not Verified
ELISA Verified:
Verified
ChIP Verified:
Verified
Dot Blot Verified:
Verified
Flow Cytometry Verified:
Not Verified
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