Granzyme B Antibody (Clone B18.1)

Granzyme B Antibody (Clone B18.1)is available at Gentaur for Next week Delivery.

Description: Granzyme B is a 27 kDa serine protease stored in granules of activated cytotoxic T cells and NK cells. Upon target cell contact, granzyme B is directionally exocytosed and assisted by perforin, enters the target cell. With its unique substrate specificity (granzyme B cleaves after Asp), granzyme B processes and activates various pro-caspases thereby inducing apoptosis in the target cell.

Immunogen Sequence:Human recombinant Granzyme B (a.a. 7-227)

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Species Reactivities:Human

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Formulation:100 µg (0.5 mg/ml) affinity purified mouse monoclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunoprecipitation, Immunohistochemistry, flow cytometry

Positive Control:Human T-cells

Application And Usages:Western blot, Immunoprecipitation, Immunohistochemistry, flow cytometry. However, the optimal conditions should be determined individually.

Handling:The antibody solution should be gently mixed before use.