Glutaredoxin 1 Antibody (Clone 28C3)

Glutaredoxin 1 Antibody (Clone 28C3)is available at Gentaur for Next week Delivery.

Description: Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH. First recovered in E.coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxido-reductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12 kDa dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress. Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

Immunogen Sequence:Recombinant human protein purified from E.coli

Target Alternative Name:Thioltransferase-1, GLRX, GRX

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect Glutaredoxin 1 in human samples.

Formulation:100 µl of antibody in HEPES with 0.15 M NaCl, 0.01 % BSA, 0.03 % sodium azide, and 50 % glycerol

Purification: Ammonium sulphate precipitation

Application:IP, ELISA.

Positive Control:WB and IP: Jurkat cell lysate

Application And Usages:IP: 1-2 µl, ELISA.

Handling:The antibody solution should be gently mixed before use.