FADD Antibody (Clone T1B)

FADD Antibody (Clone T1B)is available at Gentaur for Next week Delivery.

Description: Fas-associating death domain containing protein (FADD), also known as mediator of receptor induced toxicity (MORT1), is a 24 kDa cytosolic protein. The protein is involved in both Fas and TNF-R induced cell death pathway. FADD specifically binds to Fas, an association mediated by their homologous death domains. Overexpression of FADD induces apoptosis that can be inhibited by CrmA, a poxvirus protein that blocks both Fas- and TNF-induced cell death.

Immunogen Sequence:Recombinant human FADD

Target Alternative Name:FAS-associated death domain protein, GIG3, mgC8528, MORT1

Species Reactivities:Human, mouse, dog

Tag Line:/

Formulation:100 µg (200 µg/ml) affinity purified antibody in PBS containing 30% glycerol, 0.5% BSA and 0.01% thimerosal

Purification: Affinity purified

Application:Western blot, Immunofluorescence

Positive Control:/

Application And Usages:Western blot analysis (1-4 µg/ml). The antibody detects 28 kDa protein, corresponding to the apparent molecular weight of FADD in SDS-PAGE However, the optimal conditions should be determined individually. HeLa cell lysate can be used as a positive control.immunoblots from samples of human and mouse origins.

Handling:The antibody solution should be gently mixed before use.