E6AP Antibody

E6AP Antibodyis available at Gentaur for Next week Delivery.

Description: E6AP is an E3 ubiquitin ligase. Inheritance of a mutant maternal copy of this gene results in Angelman syndrome (AS) which is characterized by severe mental retardation, seizures, ataxia, and EEG abnormalities. E6AP interacts with the type 16 and 18 human papillomavirus E6 oncoprotein which results in the targeting of p53 for degradation via the ubiquitin-proteasome system.

Immunogen Sequence:Synthetic peptide of human E6AP

Target Alternative Name:E6AP, HPVE6AP, EPVE6AP, Human papillomavirus E6-associated protein; UBE3A, Ubiquitin-protein ligase E3A; AS, Angelman Syndrome; ANCR

Species Reactivities:Human, mouse

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Formulation:100 µl purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunoprecipitation

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Application And Usages:Western blotting (1:500 – 1:2500) and immunoprecipitation. However, the optimal concentrations should be determined individually. The antibody recognizes the E6AP of human and mouse origins. Reactivity to other species has not been tested

Handling:The antibody solution should be gently mixed before use.