DR6 Polyclonal Antibody

DR6 Polyclonal Antibodyis available at Gentaur for Next week Delivery.

Description: Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptor including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor 6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kB and JNK. DR6 is widely expressed in human tissues and cell lines.

Immunogen Sequence:Synthetic peptide surrounding amino acid 45 of human DR6 precursor.

Target Alternative Name:TNFRSF 21, TNR21, CD358

Species Reactivities:Human, Mouse, Rat

Tag Line:Polyclonal Antibody to detect DR6 in Human samples

Formulation:100 µg (0.5 mg/ml) immunoaffinity purified rabbit anti-DR6 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified rabbit IgG

Application:Western blot

Positive Control:N/A

Application And Usages:Western blot: 1-4 µg

Handling:The antibody solution should be gently mixed before use.