DAP12 Antibody

DAP12 Antibodyis available at Gentaur for Next week Delivery.

Description: DAP12 (KARAP) is a natural killer (NK) cell-expressed cell surface receptor and belongs to the immunoglobulin and C-type lectin superfamily. Unlike other members of this family which possess immunoreceptor tyrosine-based inhibitory motifs (ITIM), DAP12 contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and is present as a disulphide-bonded homodimer. Crosslinking of DAP 12-KIR complexes (membrane glycoproteins of the killer-cell inhibitory receptor family without an ITIM in their cytoplasmic domain) results in cellular activation.

Immunogen Sequence:Synthetic peptide corresponding to residues surrounding amino acids 94 of mouse DAP-12

Target Alternative Name:DAP-12, DAP 12, DAP12, TYRO protein tyrosine kinase binding protein , TYROBP

Species Reactivities:Human

Tag Line:/

Formulation:Supplied in PBS, pH 7.2, 30% glycerol, 0.5% BSA, 0.5 mM EDTA and 0.03% proclin

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually.

Handling:The antibody solution should be gently mixed before use.