Cystathionine β-Synthase Antibody

Cystathionine β-Synthase Antibodyis available at Gentaur for Next week Delivery.

Description: Cystathionine β-synthase (CBS; E.C. 4.2.1.22) is a PLP-dependent enzyme which plays a central role in sulfur amino acid metabolism in eukaryotes. CBS catalyzes condensation between serine and homocysteine to generate cystathionine, which is then further processed by cystathionine γ-lyase to yield cysteine. The gene encoding CBS is essentially linked to the genetic disorders of homocystinuria and Down syndrome. Homocystinuria is an autosomal recessive disease, characterized by high plasma levels of homocysteine, with clinical manifestations including mental retardation, thromboembolism and connective tissue defects. In addition, CBS also mediates synthesis of hydrogen sulfide by catalyzing condensation between cysteine and homocysteine. CBS is highly expressed in the nervous system, liver and kidney and is responsible for up to 95% of the H2S production in the brain.

Immunogen Sequence:Recombinant human CBS (Cat. No. 7844)

Target Alternative Name:Beta-thionase, Serine sulfhydrase, Cystathionine beta-synthase

Species Reactivities:Human

Tag Line:Polyclonal antibody to detect Lactoferrin in human samples.

Formulation:In PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin® and 50 % glycerol

Purification: Affinity purified rabbit IgG

Application:WB

Positive Control:WB: Hela cell lysates, rh-CBS

Application And Usages:WB: 1-4 µg

Handling:The antibody solution should be gently mixed before use.