CTLA4 Polyclonal Antibody

CTLA4 Polyclonal Antibodyis available at Gentaur for Next week Delivery.

Description: CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

Immunogen Sequence:KLH conjugated synthetic peptide between 50-78 amino acids from the N-terminal region of human IDDM12.

Target Alternative Name:Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, CTLA4, CD152

Species Reactivities:Human

Tag Line:Rabbit polyclonal unconjugated antibody to detect CTLA4 in human samples

Formulation:PBS with 0.09% (W/V) sodium azide

Purification: Protein A column, followed by peptide affinity purification.

Application:WB, IHC-P

Positive Control:WB

Application And Usages:WB: 1:2000IHC-P: 1:50~100

Handling:The antibody solution should be gently mixed before use