Cox-2 Antibody

Cox-2 Antibodyis available at Gentaur for Next week Delivery.

Description: COX proteins are membrane-associated heme proteins that have cyclooxygenase and peroxidase activities. These enzymes are targets of NSAID (Nonsteroidal anti-inflammatory drμgs) such as aspirin. Prostaglandins (PGs) formed by the enzymatic activity of COX-1 are primarily involved in the regulation of homeostatic functions throμghout the body, whereas PGs formed by COX-2 primarily mediate pain, fever, and inflammation. COX-1 is constitutively expressed, with particularly high expression in gastrointestinal tissues. COX-2 is induced by cytokines and mitogens and is likely to play a role in inflammatory diseases such as rheumatoid arthritis.

Immunogen Sequence:Synthetic peptide mapping to the C-terminus of human Cox-2

Target Alternative Name:Cyclooxygenase 2, PTGS2, PHS-2, COX-2, hCox-2 , PGHS-2, PGG/HS, COX2, EC 1.14.99.1

Species Reactivities:Human

Tag Line:/

Formulation:30 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 66 kDa human Cox-2. It does not cross-react with Cox-1. Jurkat cell lysate (Cat.# 2401-100) can be used as a positive control.

Handling:The antibody solution should be gently mixed before use.