CD163 Rabbit Monoclonal Antibody (Clone# 7B2), For IHC

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SKU:
A2304-50
  • CD163 Rabbit Monoclonal Antibody (Clone# 7B2), For IHC
  • CD163 Rabbit Monoclonal Antibody (Clone# 7B2), For IHC
€245
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Description

CD163 Rabbit Monoclonal Antibody (Clone# 7B2), For IHCis available at Gentaur for Next week Delivery.

Description: CD163 is a member of the scavenger receptor cysteine-rich (SRCR) superfamily that is exclusively expressed in monocytes and macrophages. It mediates the clearance of hemoglobin/haptoglobin complexes by macrophages, which may protect tissues from free hemoglobin-mediated oxidative damage. CD163 may also mediate innate immunity against bacteria, and plays a role in inflammatory responses. CD163 is upregulated in many inflammatory diseases including liver cirrhosis and rheumatoid arthritis. CD163 expression is associated with Hodgkin lymphoma, and correlates with poor survival outcomes in glioma cases. Recent studies have shown that the depletion of macrophages expressing CD163 can result in a massive recruitment of activated T cells into tumor microenvironments, suggesting a role for CD163 in tumor progression.

Immunogen Sequence:Synthesized human CD163 peptide

Target Alternative Name:Severe acute respiratory syndrome coronavirus 2; COVID-19

Species Reactivities:SARS-CoV-2

Tag Line:Plays a role in inflammatory responses

Formulation:In PBS pH 7.4, 0.02% sodium azide, 50% glycerol

Purification: Affinity purification

Application:/

Positive Control:/

Application And Usages:/

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
50 µg
Antibody Target:
Human CD163
Category:
GM-CSF
Host:
Rabbit
Antibody Type:
Monoclonal
Isotype:
IgG
Accession Number:
Q86VB7
Gene Id:
9332
Appearance:
Liquid
Form:
Rabbit monoclonal
Storage Condition:
-80ºC
Shipping Condition:
Gel Pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
FAUX
Immunofluorescence Verified:
FAUX
Immunoprecipitation Verified:
FAUX
ELISA Verified:
FAUX
ChIP Verified:
VRAI
Dot Blot Verified:
VRAI
Flow Cytometry Verified:
FAUX
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