CD144 (VE-Cadherin) Antibody

CD144 (VE-Cadherin) Antibodyis available at Gentaur for Next week Delivery.

Description: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.

Immunogen Sequence:KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD144

Target Alternative Name:Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; VE-cadherin; CD144

Species Reactivities:Human, Mouse

Tag Line:Polyclonal antibody to detect endogenous levels of CD144 in human and mouse samples.

Formulation:In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide

Purification: Affinity purified

Application:WB

Positive Control:WB: HeLa, mouse lung, mouse heart lysates

Application And Usages:WB; 1:500 – 1:2000

Handling:The antibody solution should be gently mixed before use