CBS Antibody (NT)

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SKU:
6729-100
$243
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Description

CBS Antibody (NT)is available at Gentaur for Next week Delivery.

Description: Strongly expressed in human liver and pancreas, with weaker expression in heart and brain, the cytoplasmic protein cystathionine b-synthase (CBS) operates in the first step of homocysteine transulfuration. CBS, which belongs to the cysteine synthase/cystathionine b-synthase family of proteins, catalyzes the formation of cystathionine from the thrombogenic amino acid homocysteine using pyridoxal phosphate cofactor. Allosteric activation by adenosyl-methionine regulates CBS activity. Deficiencies in CBS are associated with homocystinuria, a recessively inherited error in sulfur amino acid metabolism that affects many organs and tissues. Symptoms of homocytinuria include arteriosclerosis, thrombosis, dislocated optic lenses, mental retardation and skeletal abnormalities.

Immunogen Sequence:This CBS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human CBS.

Target Alternative Name:CBS; Cystathionine beta-synthase; Beta-thionase; Serine sulfhydrase

Species Reactivities:Human and mouse

Tag Line:Polyclonal Antibody to detect CBS in human and mouse samples.

Formulation:100 µl of antibody in PBS with 0.09% (W/V) sodium azide

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Application:Western blot, IHC, FACS, IF

Positive Control:Western blot: Raji, Rat brain and cerebellum tissue lysate, IHC: human hepatocarcinoma, FACS: Ramos cells, IF: 293 cells

Application And Usages:Western blot: ~1:1000, IHC: ~1:50–1:100, IF: ~1:10–1:50, FACS: ~1:10-1:50.

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
100 μl
Antibody Target:
CBS
Category:
CBS
Lot Number:
9D226729
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
P35520
Gene Id:
875
Concentration:
N/A
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Verified
Immunofluorescence Verified:
Verified
Immunoprecipitation Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Flow Cytometry Verified:
Verified
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