Caspase-9 Antibody

Caspase-9 Antibodyis available at Gentaur for Next week Delivery.

Description: Caspases are synthesized as inactive pro-enzymes that are processed to active form in cells undergoing apoptosis. Caspase-9 is an important member of the caspase family. Upon induction of apoptosis, Cytochrome c released from mitochondria associates with pro-caspase-9 (47 kDa) and Apaf-1. The complex processes pro-caspase-9 into a large subunit (37 kDa/17 kDa) and a small subunit (10 kDa). Cleaved caspase-9 further processes other caspases including caspase-3 and caspase-6, to initiate a caspase cascade leading to apoptosis. The affinity purified antibody recognizing the active forms of caspase-9 provides a new tool for identifying apoptotic cell populations in both tissue sections and cultured cells.

Immunogen Sequence:Recombinant protein of human Caspase-9 (Cat # 1089)

Target Alternative Name:Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6

Species Reactivities:Human

Tag Line:Polyclonal Antibody to detect Caspase-9 in human samples

Formulation:30 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin.

Purification: Affinity Purified Antibody

Application:Western blot

Positive Control:Western Blot: Recombinant protein

Application And Usages:Western blot: 1-4 µg/ml.

Handling:The antibody solution should be gently mixed before use.