Caspase-6 (Active) Antibody

Caspase-6 (Active) Antibodyis available at Gentaur for Next week Delivery.

Description: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Similar to other caspases, caspase-6 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Together with caspase-3, caspase-6 is one of the major caspases in apoptotic cells, and functions downstream of apoptosis inhibitors Bcl-2 and Bcl-xL. Caspase-6 has also been shown involving in the proteolysis of poly (ADP-ribose) polymerase (PARP) and nuclear lamin A.

Immunogen Sequence:Synthetic peptide surrounding amino acids mapping to the C-terminus of the large fragment of human caspase-6

Target Alternative Name:CASP6, CASP-6 , MCH2

Species Reactivities:Human, mouse, rat

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Formulation:100 µg (0.5 mg/ml) affinity purified rabbit anti-active caspase-6 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml) and immunofluorescence. However, the optimal conditions should be determined individually. The antibody detects the large subunit (18 kDa) of the active caspase-6. The antibody does not recognize other caspases.

Handling:The antibody solution should be gently mixed before use.