Caspase-10 Antibody

Caspase-10 Antibodyis available at Gentaur for Next week Delivery.

Description: Caspase family of cysteine proteases plays a key role in apoptosis. Caspase-10 is expressed in many tissues and cell lines. Similar to other caspases, caspase-10 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Four isoforms of caspase-10 have been identified: caspase-10a (Mch4), caspase-10b (FLICE2), caspase-10c and caspase-10d. They have the same prodomain but different mature large and small subdomains. Activated caspase-10 activates caspase-3,-4,-6,-7,-8, and –9, which are then involved in proteolytic cleavage of many cellular proteins. Caspase-10 has been shown to be involved in the Fas and TNFR1 - induced apoptosis.

Immunogen Sequence:Human recombinant Caspase-10/a (Cat # 1090A)

Target Alternative Name:FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4

Species Reactivities:Human

Tag Line:Polyclonal Antibody to detect Caspase-10 in human samples

Formulation:30 µg (0.5 mg/ml) of Caspase-10 antibody in PBS pH 7.2, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.

Purification: Affinity Purified Antibody

Application:Western blot

Positive Control:Western Blot: Recombinant protein

Application And Usages:Western blot: 1-4 µg

Handling:The antibody solution should be gently mixed before use.