Calreticulin Antibody (Clone S75)

Calreticulin Antibody (Clone S75)is available at Gentaur for Next week Delivery.

Description: Calreticulin is a calcium binding protein found in abundance in the endoplasmic reticulum and the sarcoplasmic reticulum. Like many other ER proteins, it has the conserved ER retention KDEL (Lys-Asp-Glu-Leu) sequence at its C-terminus. Calreticulin has also been detected in the nucleus and nuclear envelop. Recent studies sμggest that this soluble ER protein has a multifunctional role as it appears to be involved in calcium storage and regulation as well as having a molecular chaperone activity. Studies also sμggest its involvement in certain autoimmune diseases. Consistence with its multiple functions the calreticulin molecule appears to have a zonal character. The protein has both high and low affinity calcium binding sites.

Immunogen Sequence:Calreticulin-Maltose binding fusion protein

Target Alternative Name:CRP55, CRTC, CALR, Calregulin, cC1qR, ERp60, HACBP, RO, SSA,

Species Reactivities:Human, mouse, rat

Tag Line:/

Formulation:100 µg (200 µg/ml) protein A purified antibody in PBS containing 30% glycerol, 0.5 mg/ml BSA, and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunohistochemistry

Positive Control:/

Application And Usages:Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Other applications have not been tested.

Handling:The antibody solution should be gently mixed before use.