C-Kit/CD117 Antibody (NT)

C-Kit/CD117 Antibody (NT)is available at Gentaur for Next week Delivery.

Description: The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis, and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.

Immunogen Sequence:This c-KIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-40 amino acids from the N-terminal region of human c-KIT.

Target Alternative Name:KIT, Mast/stem cell growth factor receptor, Proto-oncogene tyrosine-protein kinase Kit

Species Reactivities:Human.

Tag Line:Polyclonal Antibody to detect c-kit/CD117 in human samples.

Formulation:50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Purification: N/A

Application:Western blot, IHC, IF.

Positive Control:Western blot: HeLa cell lysate, IHC: Breast carcinoma, FACS: Hela cells.

Application And Usages:WB: 1:1000, IHC: 1:10 – 1:50, IF: 1:10 – 1:50.

Handling:The antibody solution should be gently mixed before use.