BMI-1 Antibody

BMI-1 Antibodyis available at Gentaur for Next week Delivery.

Description: Polycomb group (PcG) genes encode chromatin proteins that are involved in the maintenance of cellular memory throμgh epigenetic chromatin modifications. Bmi-1 has been identified among the PcG genes as a potent oncogene that plays an important role in the regulation of cell proliferation by suppressing the p16-dependant pathway. Bmi-1 may be use as a therapeutic target for studying stem cell proliferation and renewal.

Immunogen Sequence:Synthetic peptide surrounding amino acid 312 of rat BMI-1

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Species Reactivities:Human, mouse, rat, bovine, dog, cat

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Formulation:30 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

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Application And Usages:Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~34 kDa of Bmi-1 in Jurkat cell lysate and rat kidney tissue lysate. Reactivity to other species has not been tested.

Handling:The antibody solution should be gently mixed before use.