ATGLAntibody

ATGLAntibodyis available at Gentaur for Next week Delivery.

Description: Triglycerides form an important energy store in many living organisms. Adipose tissue serves as the primary storage depot for triglycerides in mammals. Lipolytic enzymes mobilize triglycerides during periods of starvation to provide organisms with necessary energy. Hormone-sensitive lipase (HSL), the first identified lipolytic enzyme, hydrolyzes triglycerides in mammalian adipose tissues. Additional lipolytic enzymes, including adipose triglyceride lipase (ATGL), have also been discovered. The primary function of ATGL is to catalyze the hydrolysis of the first ester bond of lipid molecules. This enzyme may provide diglyceride substrates for HSL hydrolysis. ATGL is abundantly expressed in murine white and brown adipose tissue, and is highly substrate specific. ATGL was independently identified as desnutrin and the TG-hydrolace inducible phospholipase-A2-z.

Immunogen Sequence:Synthetic peptide corresponding to residues surrounding amino acids 385 of human ATGL

Target Alternative Name:Adipose Triglyceride Lipase, Patatin-like phospholipase domain-containing protein 2, Desnutrin, Transport-secretion protein 2, TTS2

Species Reactivities:Human, mouse, rat

Tag Line:/

Formulation:30 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunoprecipitation, and Immunohistochemistry

Positive Control:Western Blot: rat kidney tissue lysate. IHC: Heart tissue

Application And Usages:Western blotting (0.5-4 µg/ml), Immunohistochemistry (5 µg/ml), and immunoprecipitation. recognizes 54 kDa ATGL in samples from human, mouse and rat origins. However, the optimal concentrations should be determined individually.

Handling:The antibody solution should be gently mixed before use.