Anti-Wnt-1 Antibody

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SKU:
3571-30T
  • Anti-Wnt-1 Antibody
  • Anti-Wnt-1 Antibody
$88
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Description

Anti-Wnt-1 Antibodyis available at Gentaur for Next week Delivery.

Description: Wnt gene family members, including Wnt-1 throμgh Wnt-10, play a key role in regulating cellular growth and differentiation. Wnt-1 is a cysteine-rich, secreted glycoprotein that associates with cell membranes and likely functions as a key regulator of cellular adhesion. Wnt-1, which is essential for normal development of the embryonic nervous system, contributes to hyperplasia and tumorigenic progression when improperly expressed in mammary tissue. Wnt-3 is also involved in tumorigenesis and Wnt-2 and Wnt-4 may be associated with abnormal proliferation in human breast tissue. Wnt-1, Wnt-3 and Wnt-10b have been implicated along with FGF-3 in the development of mouse mammary tumor virus induced mouse mammary carcinomas.

Immunogen Sequence:Synthetic peptide surrounding amino acid 31 of human Wnt-1

Target Alternative Name:wnt1, wnt 1, wnt-1, INT 1 , INT1, wingless type MMTV integration site family member 1

Species Reactivities:Human

Tag Line:/

Formulation:100 µg (0.5 mg/ml) affinity purified rabbit Wnt-1 polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, 0.5 mM EDTA and 0.03% proclin.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml), Immunohistochemistry (10-20 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 41kDa of human Wnt-1. Reactivity to other species has not been tested.

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
30 µg
Antibody Target:
Wnt-1
Category:
Wnt
Lot Number:
50871
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
P04628
Gene Id:
7471
Concentration:
0.5 mg/ml
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
China
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Not Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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