Anti-VEGF-A Humanized Antibody

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SKU:
A2136-100
$1,768.52
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Description

Anti-VEGF-A Humanized Antibodyis available at Gentaur for Next week Delivery.

Description: The research-grade biosimilar antibody is a recombinant humanized IgG1 kappa monoclonal without an Fc fragment. This antibody binds to the receptor-binding site of vascular endothelial growth factor A (VEGF-A) and inhibits binding with its receptors (VEGFR1 and VEGFR2). This prevents VEGF-mediated proliferation and migration of endothelial cells and angiogenesis. The original drug received FDA approval in 2006 for the treatment of wet age-related macular degeneration. The drug has also been approved to treat macular edema following retinal vein occlusion, diabetic macular edema, and diabetic retinopathy.

Immunogen Sequence:Human VEGF-A

Target Alternative Name:rhuFab V2, Fab-12 variant Y0317, RhuFab, vascular endothelial growth factor A, VEGFA

Species Reactivities:Human

Tag Line:The research-grade biosimilar antibody binds to and inhibits vascular endothelial growth factor A (VEGF-A) and thus inhibits angiogenesis. The original drug received FDA approval to treat wet age-related macular degeneration, diabetic macular edema, and diabetic retinopathy

Formulation:In PBS, pH 7.5

Purification: Protein A purified

Application:In vitro

Positive Control:/

Application And Usages:In vitro studies

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
100 µg
Antibody Target:
VEGF-A
Category:
Biosimilars
Host:
Recombinant
Antibody Type:
Monoclonal
Isotype:
IgG1, kappa
Accession Number:
DB01270
Concentration:
1 mg/ml
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-80ºC
Shipping Condition:
Gel Pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
FAUX
Immunocytochemistry Verified:
FAUX
Immunofluorescence Verified:
FAUX
Immunoprecipitation Verified:
FAUX
FACS Verified:
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ELISA Verified:
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ChIP Verified:
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Dot Blot Verified:
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Flow Cytometry Verified:
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