Anti-UGT1A1 Antibody

Anti-UGT1A1 Antibodyis available at Gentaur for Next week Delivery.

Description: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate-binding site and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome.

Immunogen Sequence:Recombinant fusion protein targeting a sequence around aa 1-200 of human UGT1A1 protein

Target Alternative Name:GNT1, UGT1, UDPGT, UGT1A, HUG-BR1, BILIQTL1, UDPGT 1-1, UGT1A1, EC 2.4.1.17, UGT1-01, UGT1*1, UGT1.1, UGT-1A

Species Reactivities:Mouse, Rat

Tag Line:Affinity purified rabbit polyclonal antibody to detect UGT1A1 expression in mouse and rat samples

Formulation:In PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH 7.3

Purification: Affinity purified

Application:Western Blotting Immunofluorescence (IF)

Positive Control:/

Application And Usages:WB (1:500 - 1:2000), IF (1:50 - 1:200)

Handling:The antibody solution should be gently mixed before use.