Anti-TNF alpha (Humicade), Human IgG4 Antibody

Anti-TNF alpha (Humicade), Human IgG4 Antibodyis available at Gentaur for Next week Delivery.

Description: The antibody binds specifically to TNF-alpha, a pro-inflammatory cytokine which stimulates release of other cytiokines e.g. IL-1, IL-6 and GM-CSF as well as secretion of ICAM-1 and VCAM-1 from endothelial cells. It stimulates acute phase responses and acts as a chemoattractant for NK cells and monocytes/macrophages. The antibody reached Phase II clinical trials with Celltech, UCB.

Immunogen Sequence:Human TNF-alpha

Target Alternative Name:Tumor necrosis factor superfamily member 2, TNFSF2, TNFA

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect TNF alpha in human samples.

Formulation:200 µg affinity purified human antibody in phosphate-buffered saline (PBS) containing 0.02% Proclin 300

Purification: Affinity purified using protein A

Application:ELISA; NTRL

Positive Control:N/A

Application And Usages:/

Handling:The antibody solution should be gently mixed before use