Anti-STRADA Antibody

Anti-STRADA Antibodyis available at Gentaur for Next week Delivery.

Description: The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known.

Immunogen Sequence:Recombinant fusion protein containing a sequence corresponding to amino acids 25-210 of human STRADA (NP_699166.2).

Target Alternative Name:Stlk, PMSE, STE20-related kinase adaptor alpha, STRADA, STRAD, LYK5, NY-BR-96

Species Reactivities:Mouse

Tag Line:Affinity purified Rabbit polyclonal to STRADA

Formulation:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification: Affinity Purification

Application:Western Blotting

Positive Control:/

Application And Usages:WB 1:1000 - 1:2000

Handling:The antibody solution should be gently mixed before use.