Anti-Stathmin (STMN1) Rabbit Monoclonal Antibody (RM350)

Anti-Stathmin (STMN1) Rabbit Monoclonal Antibody (RM350)is available at Gentaur for Next week Delivery.

Description: Stathmin (STMN1), a member of the stathmin family, is also known as Leukemia-associated phosphoprotein p18, Oncoprotein 18 (Op18), Phosphoprotein p19 (pp19), Protein Pr22 and pp17, which contains one SLD (stathmin-like) domain. The function of STMN1 as an important regulatory protein of microtubule dynamics has been well-characterized. Stathmin (STMN1) interacts with two molecules of dimeric α,β-tubulin to form a tight ternary complex called the T2S complex.One mole of STMN1 binds to two moles of tubulin dimers through the stathmin-like domain (SLD).When STMN1 sequesters tubulin into the T2S complex, tubulin becomes non-polymerizable. Without tubulin polymerization, there is no microtubule assembly.STMN1 also promotes microtubule disassembly by acting directly on the microtubule ends.

Immunogen Sequence:A peptide corresponding to C-terminus of human Stathmin

Target Alternative Name:/

Species Reactivities:Human

Tag Line:Affinity purified Rabbit monoclonal to Stathmin (STMN1)

Formulation:50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Protein A affinity purified from an animal origin–free culture supernatant

Application:Western Blot: 1:2000-1:5000, IHC: 1:500-1:1000

Positive Control:/

Application And Usages:Western Blot: 1:2000-1:5000, IHC: 1:500-1:1000

Handling:The antibody solution should be gently mixed before use.