Anti-SLUG Antibody

Anti-SLUG Antibodyis available at Gentaur for Next week Delivery.

Description: Transcriptional repressor that modulates both activator-dependent and basal transcription. Involved in the generation and migration of neural crest cells. Plays a role in mediating RAF1-induced transcriptional repression of the TJ protein, occludin (OCLN) and subsequent oncogenic transformation of epithelial cells. Represses BRCA2 expression by binding to its E2-box-containing silencer and recruiting CTBP1 and HDAC1 in breast cells. In epidermal keratinocytes, binds to the E-box in ITGA3 promoter and represses its transcription. Involved in the regulation of ITGB1 and ITGB4 expression and cell adhesion and proliferation in epidermal keratinocytes.

Immunogen Sequence:Recombinant protein corresponding to human SLUG

Target Alternative Name:SLUG; SLUGH; Zinc finger protein SNAI2; Neural crest transcription factor Slug; Protein snail homolog 2

Species Reactivities:Human, Mouse, Rat

Tag Line:Polyclonal antibody to detect endogenous levels of SLUG in human, mouse and rat samples

Formulation:In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide

Purification: Affinity purified

Application:WB, IHC

Positive Control:WB: MCF7; mouse heart; rat heart; rat brain whole cell lysates, IHC: human breast cancer tissue

Application And Usages:WB; 1:500 – 1:1000; IHC; 1:100 – 1:200

Handling:The antibody solution should be gently mixed before use.