Anti-SHP2 Rabbit Monoclonal Antibody

Anti-SHP2 Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery.

Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.

Immunogen Sequence:Synthetic peptide derived from human SHP2

Target Alternative Name:BPTP3; CFC; JMML; METCDS; NS1; PTP-1D; PTP2C; SH-PTP2; SH-PTP3; SHP2; PTPN11

Species Reactivities:Human

Tag Line:Affinity purified rabbit monoclonal antibody to detect the expression of SHP2 in human samples

Formulation:In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3

Purification: Affinity purified

Application:Western Blotting

Positive Control:/

Application And Usages:WB 1:500 - 1:2000

Handling:The antibody solution should be gently mixed before use.