Anti-S1P1 Antibody

Anti-S1P1 Antibodyis available at Gentaur for Next week Delivery.

Description: Sphingosine 1-Phosphate Receptor 1 (S1P1) is a multi-pass cell membrane protein that belongs to the Gprotein coupled receptor superfamily (GPCR). S1P1 is a receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells. Clinical significance of S1P1 encompasses various diseases including cancer and multiple sclerosis. S1P1 seems to be coupled to the G(i/o) subclass of heteromeric G proteins

Immunogen Sequence:Modified 5-hydroxymethylcytosine found in DNA vertebrates

Target Alternative Name:S1P Receptor 1, S1PR1, Sphingosine 1-Phosphate Receptor 1, Endothelial differentiation GProtein Coupled Receptor 1, EDG-1.

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect S1P1

Formulation:Phosphate Buffer 10mM - NaCl 0.15M - pH 7,4

Purification: Affinity purified

Application:ELISA, IP, IF, WB, FACS

Positive Control:WB: HUVEC cells, IP: CHO-S1P1-GFP cell membranes, IF: HUVEC cells

Application And Usages:ELISA: 1:4000 to 1:10000, IP: 1-300, IF: 1:500, WB; 1:5000, FACS; 1:100

Handling:The antibody solution should be gently mixed before use