Anti-RPA70 Antibody (8C3-D12-H10)

Anti-RPA70 Antibody (8C3-D12-H10)is available at Gentaur for Next week Delivery.

Description: Replication protein A 70 kDa DNA-binding subunit plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response. It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage.

Immunogen Sequence:Recombinant human RPA70 protein fragments expressed in E.coli

Target Alternative Name:Replication protein A 70 kDa DNA-binding subunit, RP-A p70, Replication factor A protein 1, RF-A protein 1, Single-stranded DNA-binding protein, RPA1

Species Reactivities:Human, Mouse, Rat, Monkey

Tag Line:Monoclonal antibody to detect RPA70

Formulation:In PBS (pH 7.4) containing with 0.02% sodium azide and 50%

Purification: Affinity purified

Application:WB, IP, IF

Positive Control:WB: Hela, 293T, C6, 3T3 and K562 cell lysates; WB: Hela, A431, MCF7, COS7, HT1080 and K562 cell lysates; IP: HeLa cell lysates; IF: HeLa cells

Application And Usages:WB; 1:1000, IF; 1:100, IP

Handling:The antibody solution should be gently mixed before use