Anti-RET Antibody

Anti-RET Antibodyis available at Gentaur for Next week Delivery.

Description: This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related proteins to the encoded receptor stimulates receptor dimerization and activation of downstream signaling pathways that play a role in cell differentiation, growth, migration and survival. The encoded receptor is important in development of the nervous system, and the development of organs and tissues derived from the neural crest. This proto-oncogene can undergo oncogenic activation through both cytogenetic rearrangement and activating point mutations. Mutations in this gene are associated with Hirschsprung disease and central hypoventilation syndrome and have been identified in patients with renal agenesis.

Immunogen Sequence:KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human RET.

Target Alternative Name:CDHF12; CDHR16; PTC; RET51; Proto-oncogene tyrosine-protein kinase receptor Ret; Cadherin family member 12; Proto-oncogene c-Ret

Species Reactivities:Rat, Monkey, Mouse, Human

Tag Line:Affinity purified rabbit polyclonal antibody to detect RET expression in human, mouse, rat and monkey samples

Formulation:In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application:Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting

Positive Control:/

Application And Usages:WB 1:500 - 1:1000, IHC 1:100 - 1:200, IF 1:100 - 1:500

Handling:The antibody solution should be gently mixed before use.