Anti-RAD9A Antibody (3A3-A7-F8)

Anti-RAD9A Antibody (3A3-A7-F8)is available at Gentaur for Next week Delivery.

Description: Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates.

Immunogen Sequence:Recombinant human RAD9A protein fragments expressed in E.coli

Target Alternative Name:hRAD9, DNA repair exonuclease rad9 homolog A, RAD9A, Cell cycle checkpoint control protein RAD9A

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect RAD9A

Formulation:In PBS (pH 7.4) containing with 0.2% sodium azide, 50% glycerol

Purification: Affinity purified

Application:WB, IP

Positive Control:WB: HeLa, MCF7, 3T3, COS7 and Rat testis cell lysates; IP: HeLa and 3T3 cells

Application And Usages:WB; 1:500, IP

Handling:The antibody solution should be gently mixed before use