Anti-Phospho- NF kappaB p65 (Ser536) Antibody

Anti-Phospho- NF kappaB p65 (Ser536) Antibodyis available at Gentaur for Next week Delivery.

Description: NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors.

Immunogen Sequence:A synthesized peptide derived from human NF- kappaB p65 around the phosphorylation site of Serine 536

Target Alternative Name:Avian reticuloendotheliosis viral (v rel) oncogene homolog A; NF kappa B p65delta3; NFKB3; Nuclear Factor NF Kappa B p65 Subunit; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 3; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3

Species Reactivities:Human, Mouse, Rat

Tag Line:Polyclonal antibody to detect endogenous levels of NF kappaB p65 (Ser536) ) in human, mouse and rat samples

Formulation:In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Purification: Affinity purified

Application:WB, IHC, IF, IP, ELISA

Positive Control:WB: RAW 264.7 cell lysate, IHC: mouse gastric tissue, IF: Hela cells

Application And Usages:WB 1:500-1:2000 IHC 1:50-1:500 IP 1:100-1:500 IF 1：200, ELISA (peptide) 1:20000-1:40000

Handling:The antibody solution should be gently mixed before use.