Anti-PAD2 Polyclonal Antibody

Anti-PAD2 Polyclonal Antibodyis available at Gentaur for Next week Delivery.

Description: Protein arginine deiminases (PADs) are a family of guanidine-modifying enzymes that catalyze the post-translational modification of target proteins by converting arginine to citrulline. Excessive citrullination of proteins may result in disease states. PAD2 is the most widely expressed and evolutionarily conserved family member. Known substrates for PAD2 include myelin basic protein and vimentin, and PAD2 is thought to play a role in the onset and progression of neurodegenerative diseases such as Alzheimer's and multiple sclerosis. PAD2 may also play a role in transcriptional regulation as it is capable of citrullinating histone H3.

Immunogen Sequence:Recombinant Human PAD2 protein (amino acids 1 to 665)

Target Alternative Name:Peptidyl Arginine Deiminase 2; PDI2; Protein-Arginine Deiminase Type II; EC 3.5.3.15; KIAA0994; PAD-H19; PADI2

Species Reactivities:Human

Tag Line:Potentially involved in autoimmune diseases

Formulation:0.01 M PBS, pH 7.4 with 50% glycerol, 0.03% Proclin 300

Purification: Protein G purification

Application:Immunofluorescence (IF) Immunohistochemistry (IHC) Western Blotting

Positive Control:/

Application And Usages:/

Handling:The antibody solution should be gently mixed before use.