Anti-NOTCH 3 Antibody

Anti-NOTCH 3 Antibodyis available at Gentaur for Next week Delivery.

Description: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.

Immunogen Sequence:KLH-conjugated synthetic peptide encompassing a sequence within the center region of human NOTCH3

Target Alternative Name:Neurogenic locus notch homolog protein 3; Notch 3

Species Reactivities:Human, Mouse, Rat

Tag Line:Polyclonal antibody to detect endogenous levels of NOTCH 3 in human, mouse and rat samples

Formulation:In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide

Purification: Affinity purified

Application:WB

Positive Control:WB: Western blot analysis of NOTCH3 expression in A549 (A); NS-1 (B); PC12 (C) whole cell lysates.

Application And Usages:WB; 1:500 – 1:1000

Handling:The antibody solution should be gently mixed before use.