Anti-Nerve Growth Factor Receptor Antibody (IHC637)

Anti-Nerve Growth Factor Receptor Antibody (IHC637)is available at Gentaur for Next week Delivery.

Description: Nerve Growth Factor Receptor (NGFR), also known as p75, P-75NTR or CD271, is a neurotrophin receptor belonging to the tumor necrosis factor receptor family. NGFR is expressed mainly in Schwann cells and neurons, as well as a number of other non-neuronal cell types, and functions during central and peripheral nervous system development to regulate neuronal growth, migration, differentiation, and cell death. Nerve Growth Factor Receptor is also expressed in melanocytes, melanomas, neuroblastomas, pheochromocytomas, neurofibromas, neurotized nevi (type C melanocytes), and other neural crest cell or tumor derivatives. It has been suggested that NGFR may act as a tumor suppressor indicated in prostate and urothelial cancer, and Anti-Nerve Growth Factor Receptor (NGFR) is often used in adjunct with S100, to aid in the diagnosis of desmoplastic and neurotropic malignant melanomas. Anti-NGFR is also useful as an aid in the diagnosis of breast malignancy, as the antibody labels the myoepithelial cells of breast ducts and intralobular fibroblasts of breast ducts.

Immunogen Sequence:Nerve Growth Factor Receptor (NGFR)

Target Alternative Name:CD271 antigen, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, NGF receptor, low affinity nerve growth factor receptor, Nerve growth factor receptor, Nerve growth factor receptor (TNFR superfamily, member 16), p75 ICD, Gp80-LNGFR

Species Reactivities:Human

Tag Line:Monoclonal Antibody to detect Nerve Growth Factor Receptor in human samples

Formulation:Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide

Purification: Protein A/G purification

Application:IHC

Positive Control:IHC: Cervix

Application And Usages:IHC: 1:100 - 1:200

Handling:The antibody solution should be gently mixed before use