Anti-MUM1/IRF4 Rabbit Monoclonal Antibody (RM352)

Anti-MUM1/IRF4 Rabbit Monoclonal Antibody (RM352)is available at Gentaur for Next week Delivery.

Description: Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.

Immunogen Sequence:A peptide corresponding to the C-terminus of human MUM1/IRF4.

Target Alternative Name:/

Species Reactivities:Human

Tag Line:Affinity purified Rabbit monoclonal to MUM1/IRF4

Formulation:50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Protein A affinity purified from an animal origin–free culture supernatant

Application:Western Blot: 1:1000-1:2000, IHC: 1:200-1:800

Positive Control:/

Application And Usages:Western Blot: 1:1000-1:2000, IHC: 1:200-1:800

Handling:The antibody solution should be gently mixed before use.