Anti-MART1 Rabbit Monoclonal Antibody (RM333)

Anti-MART1 Rabbit Monoclonal Antibody (RM333)is available at Gentaur for Next week Delivery.

Description: MART-1 (also known as Melan-A) is a melanocyte differentiation antigen or marker recognized by autologous cytotoxic T lymphocytes. It is a membrane protein with one transmembrane peptide. Melan-A is expressed by a large proportion of melanoma tumors, both melanotic and amelanotic and by melanoma cell lines. It is present in melanocytes of normal skin and retina, nevi and in more than 85% of melanomas. Melan-A/MART-1 is not expressed by non-melanoma malignancies. It is recognized by autologous cytotoxic T lymphocytes. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. Six other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, Tyrosinase, gp100, gp75, BAGE-1, and GAGE-1.

Immunogen Sequence:A peptide corresponding to the N-terminus of human MART1 (Melanoma antigen recognized by T-cells-1).

Target Alternative Name:/

Species Reactivities:Human

Tag Line:Affinity purified Rabbit monoclonal to MART1

Formulation:50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Protein A affinity purified from an animal origin–free culture supernatant

Application:Western Blot: 1:500-1:1000, IHC: 1:500-1:1000

Positive Control:/

Application And Usages:Western Blot: 1:500-1:1000, IHC: 1:500-1:1000

Handling:The antibody solution should be gently mixed before use.