Anti-MART-1/Melan-A Antibody

Anti-MART-1/Melan-A Antibodyis available at Gentaur for Next week Delivery.

Description: MART-1 (also known as Melan-A) is a melanocyte differentiation antigen or marker recognized by autologous cytotoxic T lymphocytes. It is a membrane protein with one transmembrane peptide. Melan-A is expressed by a large proportion of melanoma tumors, both melanotic and amelanotic and by melanoma cell lines. It is present in melanocytes of normal skin and retina, nevi and in more than 85% of melanomas. Melan-A/MART-1 is not expressed by non-melanoma malignancies. It is recognized by autologous cytotoxic T lymphocytes. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. Six other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, Tyrosinase, gp100, gp75, BAGE-1, and GAGE-1.

Immunogen Sequence:Recombinant mouse MART-1 protein (Cat. No. 4824)

Target Alternative Name:Melanoma antigen recognized by T-cells 1, Antigen LB39-AA, Antigen SK29-AA, MART-1, Melan-A

Species Reactivities:Mouse

Tag Line:Polyclonal antibody to detect MART-1/Melan-A

Formulation:In PBS pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin

Purification: Affinity purified

Application:WB

Positive Control:WB: Recombinant protein

Application And Usages:WB: 1-4 µg

Handling:The antibody solution should be gently mixed before use