Anti-LAG3 Antibody (Clone# LAG3/3261)

Anti-LAG3 Antibody (Clone# LAG3/3261)is available at Gentaur for Next week Delivery.

Description: Lymphocyte-activation gene 3 (LAG3) is an immune checkpoint protein expressed on activated T cells, NK cells, B cells, and plasmacytoid dendritic cells. It acts as a negative regulator of T cells by suppressing their activation and inhibiting immune response. The T cell inhibition is caused by the binding of LAG3 to an antigen-presenting cell called MHC Class II. LAG3 is also involved in the maturation and activation of dendritic cells. LAG3 was found to be co-expressed with PD1 and caused T-cell exhaustion. LAG3 is highly expressed in tumor-infiltrating leukocytes (TILs) of various cancers, thereby making it a promising anti-cancer target.

Immunogen Sequence:Recombinant full-length human LAG3 protein

Target Alternative Name:CD223, LAG3, FDC, LAG-3

Species Reactivities:Human

Tag Line:Mouse monoclonal antibody to detect the expression of LAG3 in human samples

Formulation:In 10 mM PBS

Purification: Protein A/G purified

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Handling:The antibody solution should be gently mixed before use.