Anti-Integrin ß-5 Antibody

Anti-Integrin ß-5 Antibodyis available at Gentaur for Next week Delivery.

Description: Integrins are a family of cell surface transmembrane receptors, each consisting of an α and a β subunit that bind to extracellular matrix (ECM) proteins and cellular counter receptors and associate with the cytoskeleton. In mammals, 24 different integrins are generated through different combinations of 18 α and 8 β subunits. A number of human congenital disorders have been associated with defective integrin-mediated adhesion, including the blistering disorder junctional epidermolysis bullosa, the bleeding disorder Glanzmann’s thrombastenia, leukocyte adhesion deficiency-I (β2 integrins in leukocytes) and leukocyte adhesion deficiency-III, nephrotic syndrome and interstitial lung disease and muscular dystrophy. Integrin alpha-V/beta-5 is a receptor for fibronectin and it recognizes the sequence R-G-D in its ligand.

Immunogen Sequence:/

Target Alternative Name:Integrin ß 5, ITGB5, integrin subunit beta 5, integrin beta 5

Species Reactivities:Human

Tag Line:Polyclonal antibody to detect Integrin ß-5 in human samples

Formulation:In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin.

Purification: Affinity purified

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Handling:The antibody solution should be gently mixed before use.