Anti-Integrin β1 Antibody

Anti-Integrin β1 Antibodyis available at Gentaur for Next week Delivery.

Description: Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro). When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nodules. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1.

Immunogen Sequence:A synthesized peptide derived from human Integrin β1

Target Alternative Name:Integrin beta-1, Fibronectin receptor subunit beta, GPIIA, CD29, FNRB, MDF2, MSK12

Species Reactivities:Human, Mouse, Rat

Tag Line:Polyclonal antibody to detect endogenous levels of Integrin β1 in human, mouse and rat samples

Formulation:In phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol

Purification: Affinity purified

Application:WB, ICC/IF, ELISA

Positive Control:WB: Jurkat cells, IF/ICC: HeLa cells

Application And Usages:WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA (peptide) 1:20000-1:40000

Handling:The antibody solution should be gently mixed before use.