Anti-Integrin beta-1 Rabbit Monoclonal Antibody

Anti-Integrin beta-1 Rabbit Monoclonal Antibody is available at Gentaur for Next week Delivery.

Description: Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro). When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nodules. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1.

Immunogen Sequence:A peptide corresponding to the residues in human CD29 (Integrin beta-1).

Target Alternative Name:Integrin beta-1, Fibronectin receptor subunit beta, GPIIA, CD29, FNRB, MDF2, MSK12

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect Integrin beta-1 in human samples.

Formulation:In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Affinity purified

Application:WB, IHC

Positive Control:WB: HeLa cell lysate, IHC: human brain tissue, human colon tissue

Application And Usages:WB: 1:2000-1:4000, IHC: 1:100-1:200

Handling:The antibody solution should be gently mixed before use.