Anti-IL-6Rα (Sarilumab), Human IgG1 Antibody

Anti-IL-6Rα (Sarilumab), Human IgG1 Antibodyis available at Gentaur for Next week Delivery.

Description: The research-grade biosimilar is a fully human anti-IL-6R monoclonal IgG1 antibody that can bind to membrane as well as soluble forms of interleukin 6 receptor (IL-6R). This leads to inhibition of IL-6 mediated signaling and reduced release of CRP, serum amyloid A and fibrinogen, which are potential biomarkers of rheumatoid arthritis (RA). The original monoclonal antibody received US-FDA approval in 2017 to treat moderate to severe RA in combination with methotrexate. The original antibody is currently being evaluated for phase 3 clinical trial on COVID-19 patients

Immunogen Sequence:Sarilumab

Target Alternative Name:IL6Q, gp80, CD126, IL6RA, IL6RQ, IL-6RA, IL-6R-1, HIES5, IL-6R, IL-1Ra, IL6QTL, IL-6R-Alpha, IL6R, IL-6R 1

Species Reactivities:/

Tag Line:A fully human anti-IL-6Rα monoclonal antibody that binds membrane-bound and soluble human IL-6Rα with high affinity

Formulation:In PBS buffer, pH 7.2

Purification: /

Application:In vitro and In vivo studies

Positive Control:/

Application And Usages:In vitro and In vivo studies

Handling:The antibody solution should be gently mixed before use.