Anti-IL-6 (Siltuximab), Chimeric Antibody

Anti-IL-6 (Siltuximab), Chimeric Antibodyis available at Gentaur for Next week Delivery.

Description: The research-grade biosimilar is a chimeric (human-murine) IgG1 kappa monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells. This antibody binds to and neutralizes human IL-6, inhibits IL-6 binding to its receptor, and subsequent IL-6 signaling. The original monoclonal antibody received FDA approval to treat patients suffering from multicentric Castleman’s disease and negative for HIV and HHV-8. This monoclonal antibody has recently been investigated for the treatment of various forms of cancer such as metastatic renal cell cancer, ovarian cancer, and prostate cancer.

Immunogen Sequence:Siltuximab

Target Alternative Name:CDF, HGF, HSF, BSF2, IL-6, BSF-2, IFNB2, IFN-beta-2, IL6

Species Reactivities:Human

Tag Line:A chimeric monoclonal antibody that targets and prevents the binding of human IL-6 with its receptors, which results in decreased lymphocyte proliferation

Formulation:In PBS, pH 7.5

Purification: Protein A purified

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Handling:The antibody solution should be gently mixed before use.